Usefulness of IT knife nano for endoscopic submucosal dissection of large colorectal lesions

Aim: Endoscopic submucosal dissection (ESD) is currently widely conducted for the treatment of early gastrointestinal cancers. Due to the characteristic anatomy of the large intestine, needle-tip type devices such as Dual knife are mainly used in colorectal ESD. On the other hand, the non needle-tip type IT knife is a unique device with an insulated tip, and has been reported to be safe, efficacious and speedy when used in gastric ESD. A new model of IT knife, IT knife nanO. anticipated to be useful for esophageal and colorectal ESD has become available, but its usefulness has not been reported. Therefore, we performed this study to evaluate the usefulness of IT knife nano for ESD of large colorectal lesions.